Supporting Nerve, Joint, Heart, and Cognitive Health

  • Critical support for nerves, joints, heart, and immune system
  • Potent 1500 mg serving size of pure, genuine sustainably sourced Antarctic krill oil
  • Exceptional source of high content polyunsaturated Omega-3 fatty acids DHA and EPA
  • Contains Phospholipids for superior omega-3 bioavailability compared to fish oil
  • Industry leading 2,000 mcg of Astaxanthin, one of the most powerful natural antioxidants.
  • Extracted directly from the Antarctic Ocean using technologically advanced methods to ensure sustainability, traceability, and trust
  • Natural lemon coated encapsulation for ideal taste and enhanced shelf-life
* * SOLD OUT * *

Please Share With Family and Friends

  • Nerveology Antarctic Krill Oil


    If you are one of the estimated 40 million Americans that suffer from arthritis, peripheral nerve damage, high blood pressure or cholesterol than krill oil is the go to supplement to improve your health.

    Nerveology’s Antarctic Krill Oil Complex contains potent Omega 3 fats EPA, DHA and phospholipids that help keep your cell membranes functioning properly and improve cellular health.

    Nerveology’s Krill Oil Complex Benefits:

    • Helps reduce joint inflammation, pain, stiffness, and arthritis symptoms*
    • High bioavailability of DHA helps to protect your brain and nervous system*
    • Slows down the aging process by fighting free radicals*
    • Improves your mood and quality of life.*

    Krill Oil vs. Fish Oil

    While both fish oil and krill oil contain omega-3 fats, there are several key reasons why krill oil is superior to fish oil.

    Higher Absorption

    A 2011 study indicated that krill oil may be 48 times more potent than fish oil. * A higher potency means you need far less of it than fish oil. The secret is that the omega-3 EPA and DHA in krill oil are found in a double-chain phospholipid structure, which delivers directly to the body’s cells, allowing it to be used almost immediately. On the other hand, the omeg-3s in fish oil are in the form of triglycerides, which must go through extensive additional processing before their health benefits can be realized.

    Krill oil’s higher bioavailability allows it to quickly cross your blood-brain barrier, enabling it to reach important brain structures and improve cognitive health.

    Antioxidant Power of Astaxanthin

    Fish oil is susceptible to oxidation which can lead to the formation of harmful free radicals. A major benefit of krill oil is that it contains Astaxanthin, one of the most powerful antioxidants found in nature. Fish oil does not contain Astaxanthin. This antioxidant is nothing short of amazing as it protects Omega-3 fats from oxidation. While most krill oil formulas contain 150-300 mcg of Astaxanthin, Nerveology's Antarctic Krill Oil Complex contains an outstanding 2,000 mcg of Astaxanthin. Our high potency allows our formula to be more stable and resistant to oxidation.

    A benefit to neuropathy sufferers is that Astaxanthin can help improve nerve health by penetrating the fatty layer that wraps around nerve cells. This helps it protect both the outside and inside of the cell membrane against oxidants which can get in and damage it.

    Want more antioxidant power? Krill oil also contains the potent antioxidants vitamin E, vitamin A, vitamin D, and canthaxanthin.

    Safer and More Sustainable

    Most of the world’s fish supply is contaminated with industrial pollutants, toxins, mercury, and other heavy metals. You can put aside these concerns as the krill in our formula comes from the pure Antarctic Ocean where they are not subject to these contaminants. Krill benefit from being at the bottom of the food chain so they avoid accumulating pollutants like the bigger fish species used to make fish oil.

    Another benefit that krill has over fish is sustainability. Krill is the one of the largest biomass in the world with over 500 million tons roaming the northern seas. This makes harvesting krill a much more sustainable practice over fish.

    No Fishy Aftertaste

    A major downside to fish oil is the aftertaste. This is often cited as the main reason people avoid supplementing with this omega-3. The good news is that our lemon coated softgels and high potency of Astaxanthin, improve freshness and eliminate any fishy aftertaste commonly associated with fish oil.

    Why Nerveology Antarctic Krill Oil Complex?

    Nerveology Antarctic Krill Oil Complex is a pure, genuine, and potent 1,500 mg daily serving of high content polyunsaturated DHA and EPA Omega-3 fatty acids, encapsulated in an easy to swallow lemon coated softgel. No other brand can rival the 2,000 mcg of the powerful antioxidant Astaxanthin found in our formula, helping resist against oxidation and improving the krill oil’s longevity and stability.

    Our krill is extracted directly from the Antarctic Ocean, reducing the risk of harmful contaminants, and eliminating the concerns of overfishing. Nerveology Antarctic Krill Oil Complex goes through rigorous, third-party testing to guarantee only the highest levels of both potency and quality standards are met.

    We are confident that you will find our industry leading formula to be an essential part of supporting your nerves, joints, heart, and immune system.

    * These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

    Pure Krill Oil
    Antioxidant Fast Facts

    • 48 times the antioxidant potency of fish oil*
    • 300 times the antioxidant power of vitamin A and vitamin E
    • 47 times the antioxidant power of lutein
    • 34 times the antioxidant power of coenzyme Q-10

    Astaxanthin Fast Facts

    Astaxanthin is one of the world’s most powerful antioxidant nutrients on our planet. It has numerous proven health benefits and is often referred to as “The King of Carotenoids.” A carotenoid is a pigment that gives some of the healthiest foods their color. Everything from the lycopene in the red tomato, the beta-carotene in carrots, and the zeaxanthin and lutein in yellow corn come from Astaxanthin. Krill oil contains astaxanthin and benefits from its ability to create a special bond with the EPA and DHA. This bond allows for direct metabolism of the omega 3s, making them more bioavailable.

    Top 6 Benefits of Astaxanthin:

    • Protects healthy nerve tissue
    • Supports cognitive health during aging
    • Lessens oxidative stress to the brain
    • Helps relax blood vessels, supporting healthy blood flow, and lowering of blood pressure
    • Helps keep blood lipid levels at a normal range
    • Supports vision health

  • Nerveology Antarctic Krill Oil

    NERVEOLOGY ANTARCTIC KRILL OIL COMPLEX is proudly made in the USA from the highest quality ingredients according to cGMP regulations.

    SUGGESTED USE: As a dietary supplement take two (2) softgels one time per day a day. For best results take 20-30 min before a meal with an 8oz. glass of water or as directed by your healthcare professional.

  • Nerveology Antarctic Krill Oil Complex - Reviews

    Write a Review
    Switched from Fish Oil!
    Rick J. 11/22/2017

    I learned a lot from this site about the difference between fish and krill oil. I wish I knew this stuff before as I have been taking fish oil for years. Happy to have made the switch to Nerveology's Krill Oil

    No aftertaste!
    Bernie A. 09/13/2017

    Love the fact that this pill is easy to swallow and had not fishy aftertaste. I hated taking fish oil pills and getting those burps. No of that with this brands krill oil. They have a nice lemon taste to them.

    Omega 3 Super Pill!
    Karina M. 08/09/2017

    Great source of Omega 3s...much better than fish oil. DHA is the superhero!

    Helps me think clearer.
    Lisa H. 06/29/2017

    I have been taking this krill oil for a long time and it has helped me think clearer. I ran out for a few weeks and started to see myself get a bit cloudy at work. Just re-ordered a 6 months supply. Very nice product.

    Astaxanthin 2,000 mcg
    Sara J. 06/09/2017

    This is the only brand of krill oil that I have been able to find with 2,000 mcg of Astaxanthin. I have read the studies on antioxidant and it makes all the difference. Nerveology is an Astaxanthin powerhouse!

    Very Helpful!
    Mary W. 05/16/2017

    I called them as I needed help tracking my order. They were very helpful and help me find my package.

  • Nerveology Antarctic Krill Oil

    How should I take the Antarctic Krill Oil Complex?

    Nerveology’s Antarctic Krill Oil contains a one-month supply of 60 softgels in each container. We suggest taking one soft-gel three times each day, around 20-30 minutes before a meal, with an eight-oz. glass of water.

    What are the advantages of taking Krill Oil?

    It has been scientifically proven that Krill Oil helps to keep your cholesterol levels healthy and promotes cognitive and joint health.

    Is Krill Oil better than Fish Oil?

    Fish oil and Krill Oil both contain Omega-3 essential fatty acids in the form of EPA and DHA. The advantage of Krill Oil is that it has a higher bioavailability than that of fish oil, enabling your body to fully utilize the essential EPA and DHA quicker. Krill oil has a high amount of polyunsaturated fats in the form of phospholipids. Comparably, fish oil contains polyunsaturated fats in the form of triglycerides. Our body takes much longer to access and utilize the EPA and DHA found in triglyceride. Yet, one more benefit of krill oil is its cell rebuilding antioxidant astaxanthin, a super carotenoid.

    Does Krill Oil Leave a Fishy Aftertaste?

    It is a well-known fact that most Fish Oil supplements have a fishy flavor that hangs around after you swallow them. Our natural-lemon-coated Krill Oil capsules leave you with absolutely NO fishy aftertaste.

    Why is Astaxanthin found in Krill oil beneficial?

    Astaxanthin is a super-antioxidant found in krill oil. It is delivered by microalgae and ingested by krill shrimp, giving them their pinkish color. Astaxanthin is a carotenoid, like beta-carotene and lycopene, and is known to be one of the most powerful carotenoids. It has been shown to help improve nerve health and acts as an anti-inflammatory, essential for join health. It is also known to help enhance your skin, vitality, cardiovascular and cerebrum function. A key distinction amongst krill and fish oil is that fish oil does not contain astaxanthin.

    Is Krill Oil Safer Than Fish Oil?

    The abnormal amounts of mercury and PCBs (polychlorinated biphenyls) found in our seas contribute to the growth of destructive mercury in the ocean fish we consume. Fish oil is mostly extracted from larger fish who feed on smaller fish; which, in turn, increases their consumption of damaging mercury and PCBs. A great advantage of Nerveology’s Antarctic Krill Oil Complex is that it is sourced from the Atlantic Ocean, which is a lot less contaminated than other waters

    Krill have a shorter life expectancy and, consequently, less time to accumulate more pollutants and dangerous elements like mercury and PCBs, unlike their larger sea counterparts. Krill feed on green algae and NOT other fish, which also contributes to the fact that krill oil is, by far, a safer and more effective alternative to fish oil

    Why is Nerveology’s Antarctic Krill Oil Complex superior to others?

    Nerveology’s uniquely formulated Antarctic Krill Oil contains 1,500 mg of Pure Krill Oil, 225mg of EPA, 135 mg of DHA, 630 mg of Phospholipids and 2,000 mcg of the powerful Astaxanthin. Our powerful formula is the perfect blend to accomplish an ideal every-day dose of Omega-3 unsaturated fats.

    What if Your Krill Oil Supplement is not a good fit for me?

    We are certain that our specially-formulated Krill Oil supplement softgels will far exceed your expectations. However, should you feel that you are unhappy with our product, you can return it within 90 days to receive a full-product product refund.

    Should I be aware of ANY side effects?

    Even though there have been no “known” reactions to krill oil, our product DOES contain shellfish. If you are allergic to shellfish, please, do not take the product without consulting your doctor first.

    Can I take the Nerveology’s Krill Oil Complex even if I’m taking other medications?

    Our krill oil is a pure product of the highest quality. We do, however, strongly suggest that you consult your physician should you have any worries about adding another supplement to your day-to-day regimen.

  • Nerveology Antarctic Krill Oil

    Industry Leading Guarantee

    At Nerveology, there is nothing more important to us than our customers. We strive to provide the highest quality, most effective, and natural products available anywhere. We take our commitment to our customers with the utmost seriousness. That is why we offer an unrivaled industry-leading guarantee.

    100% Satisfaction or Your Money Back

    We want you to be 100% satisfied with each purchase and not feel rushed to decide if our products are right for you. To best support you, we offer an industry-leading, no-hassle, guarantee. If for any reason you are not 100% satisfied with your purchase, return the product, within 90-days, for a complete refund.

    Pursuit of Excellence

    At Nerveology, we pursue nothing less than absolute excellence in the products we manufacture. All of our products are made in the United States, in FDA registered labs, and under the strictest of GMP standards. Our dedicated pursuit of excellence is what drives us to ensure that only the highest quality ingredients are used in each of our products. We rigorously test every batch to ensure it is pure, potent, and safe.

    Shop with Confidence

    We want you to have complete confidence in the safety of your personal information. We use 256k-bit level SSL security and adhere to the most modern PCI compliance standards. We never sell any of your information.

    Superior Customer Service

    Nothing is more important than your health. If you have any questions or concerns about your order, please feel free to reach out to our friendly and informed customer service team. Our highly-trained team is available Mon-Fri 8AM to 8PM EST and Sat 8AM to 1PM EST. You can contact our support team by phone at (800) 501-0907 or by e-mail at

  • Nerveology Antarctic Krill Oil

    1. Konagai C, Yanagimoto K, Hayamizu K, Han L, Tsuji T, Koga Y. Effects of krill oil containing n-3 polyunsaturated fatty acids in phospholipid form on human brain function: a randomized controlled trial in healthy elderly volunteers. Clinical Interventions in Aging. 2013;8:1247-1257. doi:10.2147/CIA.S50349.

    2. Ramprasath VR, Eyal I, Zchut S, Jones PJ. Enhanced increase of omega-3 index in healthy individuals with response to 4-week n-3 fatty acid supplementation from krill oil versus fish oil. Lipids in Health and Disease. 2013;12:178. doi:10.1186/1476-511X-12-178.

    3. Ramprasath VR, Eyal I, Zchut S, Shafat I, Jones PJH. Supplementation of krill oil with high phospholipid content increases sum of EPA and DHA in erythrocytes compared with low phospholipid krill oil. Lipids in Health and Disease. 2015;14:142. doi:10.1186/s12944-015-0142-y.

    4. Jayathilake AG, Senior PV, Su XQ. Krill oil extract suppresses cell growth and induces apoptosis of human colorectal cancer cells. BMC Complementary and Alternative Medicine. 2016;16(1):328. doi:10.1186/s12906-016-1311-x.

    5. Köhler A, Sarkkinen E, Tapola N, Niskanen T, Bruheim I. Bioavailability of fatty acids from krill oil, krill meal and fish oil in healthy subjects–a randomized, single-dose, cross-over trial. Lipids in Health and Disease. 2015;14:19. doi:10.1186/s12944-015-0015-4.

    6. Woelk H, Lehrl S, Bitsch R, Kopcke W. Benfotiamine In Treatment Of Alcoholic Polyneuropathy: An 8-Week Randomized Controlled Study (Bap I Study). Alcohol and Alcoholism. 1998;33(6):631-638. doi:10.1093/alcalc/33.6.631.

    7. Berge RK, Ramsvik MS, Bohov P, et al. Krill oil reduces plasma triacylglycerol level and improves related lipoprotein particle concentration, fatty acid composition and redox status in healthy young adults - a pilot study. Lipids in Health and Disease. 2015;14:163. doi:10.1186/s12944-015-0162-7.

    8. Ierna M, Kerr A, Scales H, Berge K, Griinari M. Supplementation of diet with krill oil protects against experimental rheumatoid arthritis. BMC Musculoskeletal Disorders. 2010;11:136. doi:10.1186/1471-2474-11-136.

    9. Da Boit M, Mastalurova I, Brazaite G, McGovern N, Thompson K, Gray SR. The Effect of Krill Oil Supplementation on Exercise Performance and Markers of Immune Function. Philp A, ed. PLoS ONE. 2015;10(9):e0139174. doi:10.1371/journal.pone.0139174.

    10. Bengtson Nash SM, Schlabach M, Nichols PD. A Nutritional-Toxicological Assessment of Antarctic Krill Oil versus Fish Oil Dietary Supplements. Nutrients. 2014;6(9):3382-3402. doi:10.3390/nu6093382.

    11. Schuchardt JP, Schneider I, Meyer H, Neubronner J, von Schacky C, Hahn A. Incorporation of EPA and DHA into plasma phospholipids in response to different omega-3 fatty acid formulations - a comparative bioavailability study of fish oil vs. krill oil. Lipids in Health and Disease. 2011;10:145. doi:10.1186/1476-511X-10-145.

    12. Ulven SM, Kirkhus B, Lamglait A, et al. Metabolic Effects of Krill Oil are Essentially Similar to Those of Fish Oil but at Lower Dose of EPA and DHA, in Healthy Volunteers. Lipids. 2011;46(1):37-46. doi:10.1007/s11745-010-3490-4.

    13. Backes JM, Howard PA. Krill Oil for Cardiovascular Risk Prevention: Is It for Real? Hospital Pharmacy. 2014;49(10):907-912. doi:10.1310/hpj4910-907.

    14. Stracke H, Hammes HP, Werkmann D, et al. Efficacy of benfotiamine versus thiamine on function and glycation products of peripheral nerves in diabetic rats. Experimental and Clinical Endocrinology & Diabetes. 2001;109(06):330-336. doi:10.1055/s-2001-17399.

    15. Ulven SM, Holven KB. Comparison of bioavailability of krill oil versus fish oil and health effect. Vascular Health and Risk Management. 2015;11:511-524. doi:10.2147/VHRM.S85165.

    16. Lobraico JM, DiLello LC, Butler AD, Cordisco ME, Petrini JR, Ahmadi R. Effects of krill oil on endothelial function and other cardiovascular risk factors in participants with type 2 diabetes, a randomized controlled trial. BMJ Open Diabetes Research & Care. 2015;3(1):e000107. doi:10.1136/bmjdrc-2015-000107.

    17. Nichols PD, Kitessa SM, Abeywardena M. Commentary on a trial comparing krill oil versus fish oil. Lipids in Health and Disease. 2014;13:2. doi:10.1186/1476-511X-13-2.

    18. Seckel BR. Enhancement of peripheral nerve regeneration. Muscle & Nerve. 1990;13(9):785-800. doi:10.1002/mus.880130904.

    19. Suzuki Y, Fukushima M, Sakuraba K, Sawaki K, Sekigawa K. Krill Oil Improves Mild Knee Joint Pain: A Randomized Control Trial. Gagnier JJ, ed. PLoS ONE. 2016;11(10):e0162769. doi:10.1371/journal.pone.0162769.

    20. Wibrand K, Berge K, Messaoudi M, et al. Enhanced cognitive function and antidepressant-like effects after krill oil supplementation in rats. Lipids in Health and Disease. 2013;12:6. doi:10.1186/1476-511X-12-6.

    21. Cicero AFG, Rosticci M, Morbini M, et al. Lipid-lowering and anti-inflammatory effects of omega 3 ethyl esters and krill oil: a randomized, cross-over, clinical trial. Archives of Medical Science : AMS. 2016;12(3):507-512. doi:10.5114/aoms.2016.59923.

    22. Laidlaw M, Cockerline CA, Rowe WJ. A randomized clinical trial to determine the efficacy of manufacturers’ recommended doses of omega-3 fatty acids from different sources in facilitating cardiovascular disease risk reduction. Lipids in Health and Disease. 2014;13:99. doi:10.1186/1476-511X-13-99.

    23. Nichols PD, McManus A, Krail K, Sinclair AJ, Miller M. Recent Advances in Omega-3: Health Benefits, Sources, Products and Bioavailability. Nutrients. 2014;6(9):3727-3733. doi:10.3390/nu6093727.

    24. Bradberry JC, Hilleman DE. Overview of Omega-3 Fatty Acid Therapies. Pharmacy and Therapeutics. 2013;38(11):681-691.

    25. Skarpańska-Stejnborn A, Pilaczyńska-Szcześniak Ł, Basta P, Foriasz J, Arlet J. Effects of Supplementation with Neptune Krill Oil (Euphasia Superba) on Selected Redox Parameters and Pro-Inflammatory Markers in Athletes during Exhaustive Exercise. Journal of Human Kinetics. 2015;47:7-8. doi:10.1515/hukin-2015-0056.

    26. Senftleber NK, Nielsen SM, Andersen JR, et al. Marine Oil Supplements for Arthritis Pain: A Systematic Review and Meta-Analysis of Randomized Trials. Nutrients. 2017;9(1):42. doi:10.3390/nu9010042.

    27. Papanas N, Ziegler D. Emerging drugs for diabetic peripheral neuropathy and neuropathic pain. Expert Opinion on Emerging Drugs. 2016;21(4):393-407. doi:10.1080/14728214.2016.1257605.

    28. Papanas N, Ziegler D. Efficacy of α-lipoic acid in diabetic neuropathy. Expert Opinion on Pharmacotherapy. 2014;15(18):2721-2731. doi:10.1517/14656566.2014.972935.

    29. Mijnhout GS, Kollen BJ, Alkhalaf A, Kleefstra N, Bilo HJG. Alpha Lipoic Acid for Symptomatic Peripheral Neuropathy in Patients with Diabetes: A Meta-Analysis of Randomized Controlled Trials. International Journal of Endocrinology. 2012;2012:1-8. doi:10.1155/2012/456279.

    30. Metz J. Cobalamin Deficiency and the Pathogenesis of Nervous System Disease. Annual Review of Nutrition. 1992;12(1):59-79. doi:10.1146/annurev.nutr.12.1.59.

    31. Marchetti V, Menghini R, Rizza S, et al. Benfotiamine Counteracts Glucose Toxicity Effects on Endothelial Progenitor Cell Differentiation via Akt/FoxO Signaling. Diabetes. 2006;55(8):2231-2237. doi:10.2337/db06-0369.

    32. Loew, D. Pharmacokinetics of thiamine derivatives especially of benfotiamine. Int J Clin Pharmacol Ther. 1996;34(2):47-50.

    33. Li S-Y, Du M, Dolence EK, et al. Aging induces cardiac diastolic dysfunction, oxidative stress, accumulation of advanced glycation endproducts and protein modification. Aging Cell. 2005;4(2):57-64. doi:10.1111/j.1474-9728.2005.00146.x.

    34. Kolomoiskaia MB, Degonskii AI, Grishina RA. The myocardial contractile function and central hemodynamics of patients with insulin-dependent diabetes mellitus during treatment. Probl Endokrinol (Mosk). 1989;35(4):12-15.

    35. Kaji R, Liu Y, Duckett S, Sumner AJ. Slow recovery of central axons in acrylamide neuropathy. Muscle & Nerve. 1989;12(10):816-826. doi:10.1002/mus.880121006.

    36. Jayabalan B, Low L. Vitamin B supplementation for diabetic peripheral neuropathy. Singapore Medical Journal. 2016;57(02):55-59. doi:10.11622/smedj.2016027.

    37. Javed S, Alam U, Malik RA. Burning through the pain: treatments for diabetic neuropathy. Diabetes, Obesity and Metabolism. 2015;17(12):1115-1125. doi:10.1111/dom.12535.

    38. Javed S, Alam U, Malik RA. Burning through the pain: treatments for diabetic neuropathy. Diabetes, Obesity and Metabolism. 2015;17(12):1115-1125. doi:10.1111/dom.12535.

    39. Ide H, Fujiya S, Asanuma Y. Clinical usefulness of intrathecal injection of methylcobalamin in patients with diabetic neuropathy. Clin Ther. 1987;9(2):183-192.

    40. Ide H, Fujiya S, Asanuma Y, et al. Clinical usefulness of intrathecal injection of methylcobalamin in patients with diabetic neuropathy. Clin Ther. 1987;9(2):183-192

    41. Horowitz SH. Therapeutic strategies in promoting peripheral nerve regeneration. Muscle & Nerve. 1989;12(4):314-322. doi:10.1002/mus.880120410.

    42. Haupt E, Ledermann H, Köpcke W. Benfotiamine in the treatment of diabetic polyneuropathy – a three-week randomized, controlled pilot study (BEDIP Study). Int Journal of Clinical Pharmacology and Therapeutics. 2005;43(02):71-77. doi:10.5414/cpp43071.

    43. Harty RF, Leibach JR. Immune Disorders of the Gastrointestinal Tract and Liver. Medical Clinics of North America. 1985;69(4):675-704. doi:10.1016/s0025-7125(16)31014-8.

    44. Hammes H-P, Du X, Edelstein D, et al. Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic retinopathy. Nature Medicine. 2003;9(3):294-299. doi:10.1038/nm834.

    45. Hammes H-P, Du X, Edelstein D, et al. Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic retinopathy. Nature Medicine. 2003;9(3):294-299. doi:10.1038/nm834.

    46. Garcia-Alcala H, Vichido CIS, Macedo SI, et al. Treatment withα-Lipoic Acid over 16 Weeks in Type 2 Diabetic Patients with Symptomatic Polyneuropathy Who Responded to Initial 4-Week High-Dose Loading. Journal of Diabetes Research. 2015;2015:1-8. doi:10.1155/2015/189857.

    47. Gadau S, Emanueli C, Linthout SV, et al. Benfotiamine accelerates the healing of ischaemic diabetic limbs in mice through protein kinase B/Akt-mediated potentiation of angiogenesis and inhibition of apoptosis. Diabetologia. 2006;49(2):405-420. doi:10.1007/s00125-005-0103-5.

    48. Fadini GP, Miorin M, Facco M, et al. Circulating Endothelial Progenitor Cells Are Reduced in Peripheral Vascular Complications of Type 2 Diabetes Mellitus. Journal of the American College of Cardiology. 2005;45(9):1449-1457. doi:10.1016/j.jacc.2004.11.067.

    49. Eikelboom JW, Lonn E, Genest J, Hankey G, Yusuf S. Homocyst(e)ine and Cardiovascular Disease: A Critical Review of the Epidemiologic Evidence. Annals of Internal Medicine. 1999;131(5):363. doi:10.7326/0003-4819-131-5-199909070-00008.

    50. Dworacka M, Iskakova S, Krzyżagórska E, Wesołowska A, Kurmambayev Y, Dworacki G. Alpha-lipoic acid modifies circulating angiogenic factors in patients with type 2 diabetes mellitus. Diabetes Research and Clinical Practice. 2015;107(2):273-279. doi:10.1016/j.diabres.2014.11.005.

    51. Diglas J, Willinger C, Neu U, et al. Morbidity and mortality in type 1 and type 2 diabetes mellitus after the diagnosis of diabetic retinopathy. Clin Ther. 1992;117(45): 1703-1708.

    52. Davies M, Brophy S, Williams R, Taylor A. The Prevalence, Severity, and Impact of Painful Diabetic Peripheral Neuropathy in Type 2 Diabetes. Diabetes Care. 2006;29(7):1518-1522. doi:10.2337/dc05-2228.

    53. Chen X, Graham J, Dabbah MA, et al. Small Nerve Fiber Quantification in the Diagnosis of Diabetic Sensorimotor Polyneuropathy: Comparing Corneal Confocal Microscopy With Intraepidermal Nerve Fiber Density. Diabetes Care. 2015;38(6):1138-1144. doi:10.2337/dc14-2422.

    54. Cameron NE, Gibson TM, Nangle MR, Cotter MA. Inhibitors of Advanced Glycation End Product Formation and Neurovascular Dysfunction in Experimental Diabetes. Annals of the New York Academy of Sciences. 2005;1043(1):784-792. doi:10.1196/annals.1333.091.

    55. Bitsch R, Wolf M, Möller J, Heuzeroth L, Grüneklee D. Bioavailability Assessment of the Lipophilic Benfotiamine as Compared to a Water-Soluble Thiamin Derivative. Annals of Nutrition and Metabolism. 1991;35(5):292-296. doi:10.1159/000177659.

    56. Beyer K, Lao JI, Latorre P, et al. Methionine synthase polymorphism is a risk factor for Alzheimer disease. NeuroReport. 2003;14(10):1391-1394. doi:10.1097/01.wnr.0000073683.00308.0e.

    57. Bennett MI, Rayment C, Hjermstad M, Aass N, Caraceni A, Kaasa S. Prevalence and aetiology of neuropathic pain in cancer patients: A systematic review. Pain. 2012;153(2):359-365. doi:10.1016/j.pain.2011.10.028.

    58. Bennett GJ, Doyle T, Salvemini D. Mitotoxicity in distal symmetrical sensory peripheral neuropathies. Nature Reviews Neurology. 2014;10(8):428-428. doi:10.1038/nrneurol.2014.120.

    59. Benfotiamine.Monograph. Altern Med Rev.2006;11(3):238-242

    60. Beltramo E, Berrone E, Buttiglieri S, Porta M. Thiamine and benfotiamine prevent increased apoptosis in endothelial cells and pericytes cultured in high glucose. Diabetes/Metabolism Research and Reviews. 2004;20(4):330-336. doi:10.1002/dmrr.470.

    61. Babaei-Jadidi R, Karachalias N, Ahmed N, Battah S, Thornalley PJ. Prevention of Incipient Diabetic Nephropathy by High-Dose Thiamine and Benfotiamine. Diabetes. 2003;52(8):2110-2120. doi:10.2337/diabetes.52.8.2110.

    62. Available at: Accessed October 23, 2006.

    63. Arora S, Lidor A, Abularrage CJ, et al. Thiamine (Vitamin B1) Improves Endothelium-Dependent Vasodilatation in the Presence of Hyperglycemia. Annals of Vascular Surgery. 2006;20(5):653-658. doi:10.1007/s10016-006-9055-6.

    64. Albers JW, Pop-Busui R. Diabetic Neuropathy: Mechanisms, Emerging Treatments, and Subtypes. Current Neurology and Neuroscience Reports. 2014;14(8). doi:10.1007/s11910-014-0473-5.

    65. Alabdali M, Qrimli M, Barnett C, et al. Choosing drugs for the treatment of diabetic neuropathy. Expert Opinion on Pharmacotherapy. 2015;16(12):1805-1814. doi:10.1517/14656566.2015.1067680.

    66. Akaike A, Tamura Y, Sato Y, Yokota T. Protective effects of a vitamin B12 analog, methylcobalamin, against glutamate cytotoxicity in cultured cortical neurons. European Journal of Pharmacology. 1993;241(1):1-6. doi:10.1016/0014-2999(93)90925-8.

    67. Akaike A, Tamura Y, Sato Y, Yokota T. Protective effects of a vitamin B12 analog, methylcobalamin, against glutamate cytotoxicity in cultured cortical neurons. European Journal of Pharmacology. 1993;241(1):1-6. doi:10.1016/0014-2999(93)90925-8.

    68. Ierna M, Kerr A, Scales H, Berge K, Griinari M. Supplementation of diet with krill oil protects against experimental rheumatoid arthritis. BMC Musculoskeletal Disorders. 2010;11:136. doi:10.1186/1471-2474-11-136.

Language Picker